The Ipswich goalkeeper, who moved to Portman Road in March 2000, damaged ligaments in training last January and had an operation three months later. But despite extensive rehabilitation and consultations with medical experts, he has been advised to quit the game.
Branagan said: “A couple of weeks ago I returned to training and started to step up my work. But then I went to make a routine save again and the pain hit me, hard. It felt like a bullet had shot straight through my shoulder.
"I went to see the specialist who had done the operation on Tuesday and after talking to him for a while, he told me the injury was never going to get any better and that I had to give up playing.
"Basically, if you take the shoulder as a ball and socket joint, I have nothing to ease the movement between the two. Consequently, the pain starts when the shoulder is activated in certain ways.
"I have never been at a club where a player has had to retire from injury before so it is unknown territory for me. I have been in touch with the PFA for advice and I'm sure that will be ongoing until everything is sorted out."